About gCore

gCore, also known as The Stem Cell Genomics and Microscopy Core (SCGM) at the Sanford Consortium for Regenerative Medicine at UCSD, occupies 1,730 square feet of laboratory space dedicated to supporting research in stem cell and regenerative medicine. The core is equipped with Next-Generation Sequencing (NGS) instruments, advanced microscopy facilities, supportive laboratory instruments, and bioinformatics server computers. The NGS equipment includes PacBio Revio Long-read sequencer, Illumina NextSeq 2000 sequencer, 10x Genomics Chromium for single-cell sequencing, Nanostring GeoMX spatial genomics platform, nCounter MAX Analysis System including robotic station, and MiSeq Sequencer. The microscopy section includes the Andor Dragonfly 200 Spinning Disk Confocal Microscope, Zeiss Confocal LSM 780, Olympus Confocal FV1000 FluoView with Second Harmonic Generation for label-free imaging of protein fibers, and Bz-X  Keyence Fluorescence Microscope, all microscopes equipped for live cell and organoid imaging. Supporting instruments include the Agilent Femto Pulse and TapeStation 4200, Covaris E220 focused ultrasonicator, NanoDrop 2000 Spectrophotometer, ProFlex 3x32-well PCR System, Qubit 3.0 Fluorometer, microtome, vibratome, histology station, and tissue hoods. Computing instrumentation includes four bioinformatics servers and an IMARIS station for automated 3D microscopy analysis. 

gCore continuously cooperates with the adjacent Human Embryonic Stem Cell Core Facility (hESCCF), providing flow sorting services and UCSD The Institute for Genomic Medicine (IGM) Genomics Center, which provides Illumina NovaSeq X+ and other NGS services. 


Please be sure to include in the Acknowledgments: "We would like to thank the Stem Cell Genomics Core at the Sanford Stem Cell Institute for providing sequencing  (or microscopy) services."